A Review on Isolation Sources of Lactiplantibacillus Plantarum in Iran and Other Countries from Food Sources and with Food Applications

Document Type : Review Paper

Authors

1 Department of Biotechnology, Iranian Research Organization for Science & Technology (IROST), Tehran, Iran

2 Department of Food Science and Technology, Faculty of Pharmacy, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran

Abstract

Fermented foods are popular for their beneficial effects on human health. Fermented food products can be generally classified into five groups, including meat products, grain products, dairy products, vegetable products, bread, and fermented drinks. Lactiplantibacillus plantarum (Lb. plantarum) is one of the safest probiotic strains. Lb. plantarum is mostly isolated from dairy products as well as fermented and non-fermented products and the mucous and digestive system of humans and animals. In addition to its many uses and benefits in the industrial and clinical field, this bacterium can be used by people of different ages and with any health status because this bacterium is one of the main members of the gastrointestinal microflora. Investigations showed that Lb. plantarum has many strains, and probably in any region, certain strains of it are more abundant in the native products of that region, which may cause differences in the microbiota of people and then differences in health and behavioral characteristics. Therefore, studying the native species and strains of bacteria and changing or regulating the microbiota of people with appropriate probiotics can overcome health and behavioral problems. The result of this study can be concluded that Iran has a high potential for identifying different types of probiotics, including Lb. plantarum, due to the variety of food and dairy products.

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Abdi, R., Sheikh-Zeinoddin, M., Soleimanian-Zad, S. (2006). Identification of lactic acid bacteria isolated from traditional Iranian Lighvan cheese. Pakistan Journal of Biological Sciences, 9(1), 99-103. https://doi.org/10.3923/pjbs.2006.99.103
Adiyoga, R., Arief, I. I., Budiman, C., Abidin, Z. (2022). In vitro anticancer potentials of Lactobacillus plantarum IIA-1A5 and Lactobacillus acidophilus IIA-2B4 extracts against WiDr human colon cancer cell line. Food Science and Technology, 42, e87221.
 Afshari, A., Hashemi, M., Tavassoli, M., Eraghi, V., Noori, S. M. A. (2022). Probiotic bacteria from 10 different traditional Iranian cheeses: Isolation, characterization, and investigation of probiotic potential. Food Science & Nutrition, 10(6), 2009-2020. https://doi.org/10.1002/fsn3.2817.
 Amor, K. B., Vaughan, E. E., de Vos, W. M. (2007). Advanced Molecular Tools for the Identification of Lactic Acid Bacteria1. The Journal of Nutrition, 137(3), 741S-747S.
 Bahadori, Z., Norozi, J., Akhavan, Sepahi A., Sabzevari, J., Razavipoor, R. (2010). Study of β-galactosidase activity in Lactobacilli separated from milk and cheese by biochemical and PCR methods. Yafteh, 12(43), 39-48.
 Bansal, A. K. (2005). Bioinformatics in microbial biotechnology–a mini review. Microbial Cell Factories, 4, 1-11.
 Bringel, F., Castioni, A., Olukoya, D., Felis, G., Torriani, S., Dellaglio, F. (2005). Lactobacillus plantarum subsp. argentoratensis subsp. nov., isolated from vegetable matrices. International Journal of Systematic and Evolutionary Microbiology, 55, 1629-1634. https://doi.org/10.1099/ijs.0.63333-0
 Burns, P., Cuffia, F., Milesi, M., Vinderola, G., Meinardi, C., Sabbag, N., Hynes, E.  (2011). Technological and probiotic role of adjunct cultures of non-starter lactobacilli in soft cheeses. Food Microbiolgy, 30(1), 45-50. https://doi.org/10.1016/j.fm.2011.09.015
 Camu, N., De Winter, T., Verbrugghe, K., Cleenwerck, I., Vandamme, P., JS, T., Vancanneyt., M, De Vuyst, L. (2007). Dynamics and biodiversity of populations of lactic acid bacteria and acetic acid bacteria involved in spontaneous heap fermentation of cocoa beans in Ghana. Appl Environ Microbiology, 73(6), 1809-1824. https://doi.org/10.1128/aem.02189-06
 Cho, G. S., Hanak, A., Huch, M., Holzapfel, W. H., Franz, C. M. A. P. (2010). Investigation into the Potential of Bacteriocinogenic Lactobacillus plantarum BFE 5092 for Biopreservation of Raw Turkey Meat. Probiotics Antimicrob Proteins, 2(4), 241-249. https://doi.org/10.1007/s12602-010-9053-4
 Chuah LiOon, C. L., Foo HooiLing, F. H., Loh TeckChwen, L. T., Noorjahan Banu, M., Yeap SweeKeong, Y. S., Nur Elina, A., Raha Abdul Rahim, R. A. R., Khatijah Yusoff, K. Y. (2019). Postbiotic metabolites produced by Lactobacillus plantarum strains exert selective cytotoxicity effects on cancer cells. BMC Complementary and Alternative Medicine, 19, 1-12.
 Corsetti, A., Valmorri, S. (2011). Lactobacillus ssp.: Lactobacillus plantarum. In Encyclopedia of Dairy Sciences, 2nd ed., Academic Press Ltd, Vol 3, pp 111-113.
 Crowly, S., Mahony, J., Van Sinderen, D. (2012). Comparative analysis of two antifungal Lactobacillus plantarum isolates and their application as bioprotectants in refrigerated foods. Journal of Applied Microbiology, 113(6), 1417-1427. https://doi.org/10.1111/jam.12012.
 De Angelis, M., de Candia, S., Calasso, MP., Faccia, M., Guinee, TP., Simonetti, MC., Gobbetti M. (2008). Selection and use of autochthonous multiple strain cultures for the manufacture of high-moisture traditional Mozzarella cheese. International Journal of Food Microbiology, 15(2), 123-132. https://doi.org/10.1016/j.ijfoodmicro.2008.03.043.
 Duan, Y., Tan, Z., Wang, Y., Li, Z., Li, Z., Qin, G., Huo, Y., Cai, Y. (2008). Identification and characterization of Lactic Acid Bacteria isolated from Tibetan Qula cheese. The Journal of General and Applied Microbiology, 54(1), 51-60. https://doi.org/10.2323/jgam.54.51
 Edalatian, M. R., Najafi, M. B. H., Mortazavi, S. A., Alegría, Á., Nassiri, M. R., Bassami, M. R., Mayo, B. (2012). Microbial diversity of the traditional Iranian cheeses Lighvan and Koozeh, as revealed by polyphasic culturing and culture-independent approaches. Dairy Science & Technology, 92(1), 75-90. https://doi.org/10.1007/s13594-011-0045-2 
 Echegaray, N., Yilmaz, B., Sharma, H., Kumar, M., Pateiro, M., Ozogul, F., Lorenzo, J. M. (2023). A novel approach to Lactiplantibacillus plantarum: From probiotic properties to the omics insights. Microbiological Research, 268, 127289. https://doi.org/10.1016/j.micres.2022.127289
 Ershadian, M., Arbab Soleimani, N., Ajodani Far, H., Vaezi Khakhki, M. (2015). The Co-aggregation effects of probiotic lactobacillus against some pathogenic bacteria. Iranian Journal of Medical Microbiology, 9(3), 14-22.
 Escalante-Minakata, P., Blaschek, H. P., Barba de la Rosa, A. P., Santos, L., De León-Rodríguez, A. (2008). Identification of yeast and bacteria involved in the mezcal fermentation of Agave salmiana. Letters in Applied Microbiology, 46(6), 626-630. https://doi.org/10.1111/j.1472-765X.2008.02359.x
 Esmaeili, T., Emami, Z., Ahadi, A. M., Shahanipour, K., Shafighi, M. (2012). Identification of Lactobacillus plantarum isolated from olive by PCR-RFLP. Jornal of Microbial Biotechnology, 4, 21-28.
 Essid, I., Medini, M., Hassouna, M. (2009). Technological and safety properties of Lactobacillus plantarum strains isolated from a Tunisian traditional salted meat. Meat science, 81(1), 203-208. https://doi.org/10.1016/j.meatsci.2008.07.020
 Farahbakhsh, M., Hakimi, H., Bahram Abadi, R., Zolfaghari, M., Doraki, N. (2013). Isolation of Probiotic Lactobacilli from Traditional Yogurts Produced in Rural Areas of Rafsanjan and their Antimicrobial Effects. Journal of Rafsanjan University of Medical Sciences, 12 (9), 733-746.
 Feld, L., Bielak, E., Hammer, K., Wilcks, A. (2009). Characterization of a small erythromycin resistance plasmid pLFE1 from the food-isolate Lactobacillus plantarum M345. Plasmid, 61(3), 159-170. https://doi.org/10.1016/j.plasmid.2009.01.002
 Filannino, P., De Angelis, M., Di Cagno, R., Gozzi, G., Riciputi, Y., Gobbetti, M. (2018). How Lactobacillus plantarum shapes its transcriptome in response to contrasting habitats. Environmental Microbiology, 20(10), 3700-3716. https://doi.org/10.1111/1462-2920.14372
 Fontán, M., Lorenzo, J. M., Martínez, S., Franco, I., Carballo, J. (2007). Microbiological characteristics of Botillo, a Spanish traditional pork sausage. LWT - Food Science and Technology, 40, 1610-1622. https://doi.org/10.1016/j.lwt.2006.10.007
 Gholipour, F., Amini, M., Baradaran, B., Mokhtarzadeh, A., Eskandani, M. (2023). Anticancer properties of curcumin-treated Lactobacillus plantarum against the HT-29 colorectal adenocarcinoma cells. Scientific Reports, 13(1), 2860.
 Guidone, A., Zotta, T., Ross, R. P., Stanton, C., Rea, M. C., Parente, E., Ricciardi, A. (2014). Functional properties of Lactobacillus plantarum strains: A multivariate screening study. LWT - Food Science and Technology, 56(1), 69-76. https://doi.org/https://doi.org/10.1016/j.lwt.2013.10.036
 Hamon, E., Horvatovich, P., Izquierdo, E., Bringel, F., Marchioni, E., Aoudé-Werner, D., Ennahar, S. (2011). Comparative proteomic analysis of Lactobacillus plantarum for the identification of key proteins in bile tolerance. BMC Microbiology, 11, 1-11. https://doi.org/10.1186/1471-2180-11-63
 Hernández, D., Cardell, E., Zárate, V. (2005). Antimicrobial activity of lactic acid bacteria isolated from Tenerife cheese: initial characterization of plantaricin TF711, a bacteriocin-like substance produced by Lactobacillus plantarum TF711. Journal of Applied Microbiology, 99(1), 77-84. https://doi.org/10.1111/j.1365-2672.2005.02576.x
 Isa, J. K., Razavi, S. H. (2017). Characterization of Lactobacillus plantarum as a potential probiotic in vitro and use of a dairy product (yogurt) as food carrier. Applied Food Biotechnology, 4(1), 11-18.
 Kaban, G., Kaya, M. (2009). Effects of Lactobacillus plantarum and Staphylococcus xylosus on the Quality Characteristics of Dry Fermented Sausage “Sucuk”. Journal of Food Science, 74(1), S58-S63. https://doi.org/10.1111/j.1750-3841.2008.01014.x
 Kawashima, T., Hayashi, K., Kosaka, A., Kawashima, M., Igarashi, T., Tsutsui, H., Tsuji, NM., Nishimura, I, Hayashi T, Obata, A. (2011). Lactobacillus plantarum strain YU from fermented foods activates Th1 and protective immune responses. International immunopharmacology, 11(12), 2017-2024. https://doi.org/10.1016/j.intimp.2011.08.013
 Kim, B. G., Choi, S. Y., Kim, M. R., Suh, H. J., Park, H. J. (2010). Changes of ginsenosides in Korean red ginseng (Panax ginseng) fermented by Lactobacillus plantarum M1. Process Biochemistry, 45(8), 1319-1324. https://doi.org/10.1016/j.procbio.2010.04.026
 Koleva, P., Georgieva, R., Nikolova, D., Danova, S. (2009). Lactic Acid Microflora of Bulgarian Milk Products From Mountain Regions. Biotechnology, Biotechnological Equipment, 23(1), 856-860. https://doi.org/10.1080/13102818.2009.10818557
 Kuda, T., Kaneko, N., Yano, T., Mori, M. (2010). Induction of superoxide anion radical scavenging capacity in Japanese white radish juice and milk by Lactobacillus plantarum isolated from aji-narezushi and kaburazushi. Food Chemistry, 120, 517-522. https://doi.org/10.1016/j.foodchem.2009.10.046
 Kumar, H., Rangrez, A. Y., Dayananda, K. M., Atre, A. N., Patole, M. S., Shouche, Y. S. (2011). Lactobacillus plantarum (VR1) isolated from an ayurvedic medicine (Kutajarista) ameliorates in vitro cellular damage caused by Aeromonas veronii. BMC Microbiolgy, 11, 152. https://doi.org/10.1186/1471-2180-11-152
 Lashani, E., Davoodabadi, A., Soltan Dallal, M. (2018). Antimicrobial Effects of Lactobacillus Plantarum and Lactobacillus Paracasei Isolated from Honey against Staphylococcus Aureus. Journal of Babol University of Medical Sciences, 20 (3), 44-49. https://doi.org/10.18869/acadpub.jbums.20.3.44
 Liu, H., Xu, W., Luo, Y., Tian, H., Wang, H., Guo, X., Yuan, Y., Huang, K. (2011). Assessment of tolerance to multistresses and in vitro cell adhesion in genetically modified Lactobacillus plantarum 590. Antonie Van Leeuwenhoek, 99(3), 579-589. https://doi.org/10.1007/s10482-010-9529-y
 Mäkimattila, E., Kahala, M., Joutsjoki, V. (2010). Characterization and electrotransformation of Lactobacillus plantarum and Lactobacillus paraplantarum isolated from fermented vegetables. World Journal of Microbiology and Biotechnology, 27, 371-379. https://doi.org/10.1007/s11274-010-0468-6
 Melgar-Lalanne, G., Rivera-espinoza, Y., Hernández-Sánchez, H. (2012). Lactobacillus plantarum: An overview with emphasis in biochemical and healthy properties. Pérez Campos A., Mena AL (eds). Nova Publishing, New York, USA, pp 1-31.
 Mirdamadi, S., Tangestani, M. (2011). Screening and characterization of bacteriocins produced by some strains of Lactobacillus spp isolated from Iranian Dairy Products. Food Hygiene, 1(3), 55-70.
 Morales, F., Morales, J. I., Hernández, C. H., Hernández-Sánchez, H. (2011). Isolation and partial characterization of halotolerant lactic acid bacteria from two Mexican cheeses. Applied Biochemistry and Biotechnology, 164(6), 889-905. https://doi.org/10.1007/s12010-011-9182-6
 Mosallami, S., Parsaeimehr, M., Ahmadi, Hamedani., M, Jebelli Javan, A., Moezifar, M. (2020). Effect of probiotic Lactobacillus plantarum ktbs2 on serum total oxidant and antioxidant, oxidative stress index and some biochemical parameters in induced diabetic rats. Iranian Veterinary Journal, 16(3), 94-105.
 Motahari, P., Mirdamadi, S., Kiani Rad, M. (2016). A sequential statistical approach towards an optimized production of bacteriocin by Lactobacillus pentosus TSHS. Journal of Food Processing and Preservation, 40(6), 1238-1246. https://doi.org/10.1111/jfpp.12708.
 Müller, D. M., Carrasco, M. S., Tonarelli, G. G., Simonetta, A. C. (2009). Characterization and purification of a new bacteriocin with a broad inhibitory spectrum produced by Lactobacillus plantarum lp 31 strain isolated from dry-fermented sausage. Journal of Applied Microbiology, 106(6), 2031-2040. https://doi.org/10.1111/j.1365-2672.2009.04173.x
 Nanda, D. K., Tomar, S. K., Singh R, Mal G, Sing P, Arora D. K, Joshi B. K, Chaudarty R, Kumar, D. (2011). Phenotypic and genotypic characterisation of Lactobacilli isolated from camel cheese produced in India. International Journal of Dairy Technology, 64(3), 437-443. https://doi.org/10.1111/j.1471-0307.2011.00695.x
 Narimani, T., Tarinejad, A., Hejazi, M. A. (2012). Isolation and identification of lactic acid bacteria from traditional dairy products of Kleibar, Heris and Varzaghan. Journal of Food Hygiene, 3(11), 23-37.
 Nespolo, C. R, Brandelli, A. (2010). Production of bacteriocin-like substances by lactic acid bacteria isolated from regional ovine cheese. Brazilian Journal of Microbiology, 41(4), 1009-1018. https://doi.org/10.1590/s1517-838220100004000020
 Nieto-Arribas, P., Poveda, J., seseña, S., Palop, L., & Cabezas, L. (2009). Technological characterization of Lactobacillus isolates from traditional Manchego cheese for potential use as adjunct starter cultures. Food Control, 20, 1092-1098. https://doi.org/10.1016/j.foodcont.2009.03.001
 Nouri, S., Nazeri, S., Hosseyni, P. (2018). Biochemical and molecular identification of probiotic bacteria, "Lactobacillus plantarum", isolated from apple vinegar. Cellular and Molecular Research, 31(1), 79-92.
 O’Donnell, S. T., Ross, R. P., Stanton, C. (2020). The progress of multi-omics technologies: determining function in lactic acid bacteria using a systems level approach. Frontiers in Microbiology, 10, 483666. https://doi.org/10.3389/fmicb.2019.03084
 Partovi, R., Gandomi, H., Akhondzadeh Basti, A. (2017). Technological properties of Lactobacillus plantarum strains isolated from Siahmazgi cheese. Journal of Food Process. Preservation, 42(6), e13629. https://doi.org/10.1111/jfpp.13629.
 Pepe, O., Blaiotta, G., Anastasio, M., Moschetti, G., Ercolini, D., Villani, F. (2004, Aug). Technological and molecular diversity of Lactobacillus plantarum strains isolated from naturally fermented sourdoughs. Systematic and Applied Microbiology, 27(4), 443-453. https://doi.org/10.1078/0723202041438446
 Pourabdi Sarabi, P., Tarinejad, A., Hejazi, MA., Majidi, M. (2020). Tracing Of Iia And Iib Bacteriocins In Native Strains Of Lactobacillus Isolated From Traditional Dairy Products. Journal of Food Hygiene, 10 (39), 67-81.
 Rajabloo, S., Sharifan, A., Aminafshar, M., Jamalifar, H., Fazwli., M. (2012). Production Of Probiotic Pickled Cucumber Using Selected Native Lactobacillus Plantarum. Journal of Food Technology & Nutrition Sciences, 9(34), 65-72.
 Rao, K. P., Chennappa, G., Suraj, U., Nagaraja, H., Raj, A. P., Sreenivasa, M. Y. (2015). Probiotic potential of lactobacillus strains isolated from sorghum-based traditional fermented food. Probiotics Antimicrob Proteins, 7(2), 146-156. https://doi.org/10.1007/s12602-015-9186-6
 Rojo-Bezares, B., Sáenz, Y., Poeta P, Zarazaga M, Ruiz-Larrea F, Torres, C. (2006). Assessment of antibiotic susceptibility within lactic acid bacteria strains isolated from wine. International Journal of Food Microbiology, 111(3), 234-240. https://doi.org/10.1016/j.ijfoodmicro.2006.06.007
 Rouhi, A., Falah, F., Azghandi, M., Behbahani, B. A., Mortazavi, S. A., Tabatabaei-Yazdi, F., Vasiee, A. (2024). Investigating the effect of Lactiplantibacillus plantarum TW57-4 in preventing biofilm formation and expression of virulence genes in Listeria monocytogenes ATCC 19115. LWT, 191, 115669.
 Saboktakin-Rizi, M., Alizadeh, Behbahani B, Hojjati M, & Noshad, M. (2021). Identification of Lactobacillus plantarum TW29-1 isolated from Iranian fermented cereal-dairy product (Yellow Zabol Kashk): probiotic characteristics, antimicrobial activity and safety evaluation. Journal of Food Measurement and Characterization, 15, 2615–2624. https://doi.org/10.1007/s11694-021-00846-5.
 Sadeghi-Aliabadi, H., Mohammadi, F., Fazeli, H., Mirlohi, M. (2014). Effects of Lactobacillus plantarum A7 with probiotic potential on colon cancer and normal cells proliferation in comparison with a commercial strain. Iranian Journal of Basic Medical Sciences, 17(10), 815-819.
 Samanarad, Z., AkhavaneSepahy, A., Bikhof Torbati, M. (2023). Investigating the synergism of lactobacillus plantarum cell lysate supernatant and carboplatin on the induction of cell death and expression of Bax and Bcl-2 genes in the SK-OV-3 cell line. Journal of Microbial Biology, 12(48), 51-64.
 Samappito, W., Leenanon, B., Levin, R. E. (2011). Microbiological Characteristics of ''Mhom'', a Thai Traditional Meat Sausage. Journal of Food Science., 5. https://doi.org/10.2174/1874256401105010031
 Samelis, J., Bleicher, A., Delbès-Paus, C., Kakouri, A., Neuhaus, K., Montel, M. C. (2011). FTIR-based polyphasic identification of lactic acid bacteria isolated from traditional Greek Graviera cheese. Food Microbiology, 28(1), 76-83. https://doi.org/10.1016/j.fm.2010.08.009.
 Shah, A. M., Tarfeen, N., Mohamed, H., Song, Y. (2023). Fermented foods: Their health-promoting components and potential effects on gut microbiota. Fermentation, 9(2). https://doi.org/10.3390/fermentation9020118
 Soleymanzadeh, N., Mirdamadi, S., & Kianirad, M. (2017). Incidence of virulence determinants and antibiotic resistance in lactic acid bacteria isolated from Iranian traditional fermented camel milk (Chal). Journal of Food Biosciences and Technology, 7(2), 1-8.
 Tajabadi, N., Mardan, M., Saari, N., Mustafa, S., Bahreini, R., Manap, M. Y. A. (2013). Identification of Lactobacillus plantarum, Lactobacillus pentosus and Lactobacillus fermentum from honey stomach of honeybee. Brazilian Journal of Microbiology, 44(3), 717 -722.
 Tallon, R., Arias, S., Bressollier, P., Urdaci, M. C. (2007). Strain- and matrix-dependent adhesion of Lactobacillus plantarum is mediated by proteinaceous bacterial compounds. Journal of Applied Microbiology, 102(2), 442-451. https://doi.org/10.1111/j.1365-2672.2006.03086.x
 Tanganurat, W., Quinquis, B., Leelawatcharamas, V., Bolotin, A. (2009). Genotypic and phenotypic characterization of Lactobacillus plantarum strains isolated from Thai fermented fruits and vegetables. Journal of Basic Microbiology, 49(4), 377-385. https://doi.org/10.1002/jobm.200800185
 Todorov, S. D., Ho, P., Vaz-Velho, M., Dicks,  L. M. T. (2010). Characterization of bacteriocins produced by two strains of Lactobacillus plantarum isolated from Beloura and Chouriço, traditional pork products from Portugal. Meat Science, 84, 334-343.
 Todorov, S. D., Dicks,  L. M. T. (2006). Effect of medium components on bacteriocin production by Lactobacillus plantarum strains ST23LD and ST341LD, isolated from spoiled olive brine. Microbiological Research, 161, 102-108. 
 Todorov, S. D., Nyati, H., Meincken, M., Dicks,  L. M. T. (2007). Partial characterization of bacteriocin AMA-K, produced by Lactobacillus plantarum AMA-K isolated from naturally fermented milk from Zimbabwe. Food Control, 18, 656-664. 
 Todorov, S. D., van Reenen, C. A., Dicks,  L. M. T. (2004). Optimization of bacteriocin production by Lactobacillus plantarum ST13BR, a strain isolated from barley beer.  The Journal of General and Applied Microbiology, 50, 149-157.
 Van Hoorde, K., Verstraete, T., Vandamme, P., Huys, G. (2008). Diversity of lactic acid bacteria in two Flemish artisan raw milk Gouda-type cheeses. Food Microbiology, 25(7), 929-935. https://doi.org/10.1016/j.fm.2008.06.006
 Wang, Y., Li, C., Liu, P., Ahmed, Z., Xiao, P., Bai, X. (2010). Physical characterization of exopolysaccharide produced by Lactobacillus plantarum KF5 isolated from Tibet Kefir. Carbohydrate Polymers, 82(3), 895-903.
 Xie, Y., An, H., Hao, Y., Qin, Q., Huang, Y., Luo, Y., Zhang, L. (2011). Characterization of an anti-Listeria bacteriocin produced by Lactobacillus plantarum LB-B1 isolated from koumiss, a traditionally fermented dairy product from China. Food Control, 22, 1027-1031. https://doi.org/10.1016/j.foodcont.2010.12.007
 Yeoh, C. Y., Cheah, Y. K. (2020). Bioinformatics in the identification of microorganisms. Life Sciences, Medicine and Biomedicine, 4(1).  https://doi.org/10.28916/lsmb.4.9.2020.64
 Yilmaz, B., Bangar, S. P., Echegaray, N., Suri, S., Tomasevic, I., Manuel Lorenzo, J., Melekoglu, E., Rocha, J. M., Ozogul, F. (2022). The impacts of Lactiplantibacillus plantarum on the functional properties of fermented foods: A review of current knowledge. Microorganisms, 10(4), 826. https://doi.org/10.3390/microorganisms10040826
 Yin, S., Hao, Y., Zhai, Z., Li, R., Huang, Y., Tian, H., Luo, Y. (2008). Characterization of a cryptic plasmid pM4 from Lactobacillus plantarum M4. FEMS Microbiology letters, 285(2), 183-187.https://doi.org/10.1111/j.1574-6968.2008.01229.x
 Zago, M., Fornasari, ME., Carminati, D., Burns, P., Suàrez, V., Vinderola, G., Reinheimer, J.,  Giraffa, G. (2011). Characterization and probiotic potential of Lactobacillus plantarum strains isolated from cheeses. Food Microbiolgy, 28 (5), 1033-1040. DOI: 10.1016/j.fm.2011.02.009
 Zamani, H. (2016). Isolation Of a Potentially Probiotic Lactobacillus Plantarum from Siahmezgi Cheese and Its Characterization as a Potentially Probiotic. Biological Journal of Microorganism, 4(16), 97-108.
 Zheng, J., Wittouck, S., Salvetti, E., Franz, C. M., Harris, H. M., Mattarelli, P., O'Toole, P.,  Pot , B.,  Vandamme, P.,  Walter, J.,  Koichi Watanabe, K., Wuyts, S., Felis, G. E., Gänzle , M. G., Lebeer, S. (2020). A taxonomic note on the genus Lactobacillus: Description of 23 novel genera, emended description of the genus Lactobacillus Beijerinck 1901, and union of Lactobacillaceae and Leuconostocaceae. International Journal of Systematic and Evolutionary Microbiology, 70(4), 2782-2858. https://doi.org/10.1099/ijsem.0.004107.
 Zhou, J. S., Pillidge, C. J., Gopal, P. K., Gill, H. S. (2005). Antibiotic susceptibility profiles of new probiotic Lactobacillus and Bifidobacterium strains. International Journal of Food Microbiology, 1(2), 211-217. https://doi.org/10.1016/j.ijfoodmicro.2004.05.011.